Jess automates the protein separation & immunodetection of traditional Western blotting. And obviously I like getting results the same day rather than having to wait two days", Emma Wilson (ne Humphrey), Ph.D., Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates. Avantor has the resources to make your Chromatography or Mass Spectrometry applications run efficiently and effectivelyfrom the measuring apparatus needed for chromatography, or the proteins used to fulfill sample manipulation during mass spectrometry. ", Melyssa Bratton, Ph.D., Get the picture with her chemiluminescent blot imaging system. 2 CHEMILUMINESCENCE DETECTION RNase A Working with low abundance targets or precious samples? Excitation of the fluorophores releases photons and the emission spectra is detected and recorded by a CCD camera in a series of images over time. As our customers needs have evolved, so have our capabilities. VWR supports you in your autosampler vial selection process through on-site consultations with our Chromatography Specialists, and providing samples when needed. In Stock. This page is dedicated to featured products, resources, and valuable information pertaining to this rapidly developing area. Please sign in to view account pricing and product availability. This technology has made it possible for small research labs to compete with the pace that research is conducted in large labs or companies. Your session has expired. This is something I wouldnt even try with traditional Western blots. Want to analyze expression changes between samples or compare runs? AUTOMATED IMMUNOASSAYS AND TOTAL PROTEIN NORMALIZATION EQUALS BETTER QUANTIFICATION Pan AKT Probe 2: Total Protein Total Protein Immunoassay and total protein detection HOW DOES JESS WORK? Avantor helps keep you safe with a robust line of safety products and personal protective equipment -- from waste bins to safety signs. With her 13 and 25 sample capillary cartridges you'll get the throughput you need, with minimum hands-on time. 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We appreciate your feedback. Our portfolio is used in virtually every stage of the most important research, development and production activities in the industries we serve. Easy access to products and protocols for research use only in the identification of 2019-nCoV based on Centers for Disease Control and Prevention (CDC) recommendations. VWR provides the cell culture community with access to the most reliable supply of exceptional quality Fetal Bovine Serum: VWR Life Science Seradigm. We have become experts in scientific operations, improving performance with sophisticated solutions and providing guidance on best practices. Jess allows me to accurately assess drug compound potency, and with its high throughput ability I can screen multiple compounds quickly and efficiently. Exceptional skid resistance, both wet and dry, for dirty jobs and controlled environments. Got a lot of samples? VWR is your complete source for workplace supplies. Pack contains enough reagents to obtain 200 Simple Western data points. Setting the standard in quality research reagents for over 30 years, A trusted leader in quality life science reagents, Your trusted supplier for innovative and high performance life science reagents, Proprietary systems and consumables for simpler, more quantitative and affordable protein analysis, Proprietary RNAscope technology capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity, A world leader in developing liquid biopsy based diagnostics, 614 McKinley Place NE Or get info on protein abundance, isoform and size all at once. With Jess's chemiluminescent detection, you'll get picogram level sensitivity letting you maximize the data you get from your sample. Jess automates the protein separation and immunodetection of traditional western blotting eliminating many of the tedious error-prone steps. I really like this system over traditional Western. Get trusted safety products from Avantor. NC1839594 The results are much better too, given that it removes the blotting step all together. Senior Research Scientist, Aurelia Bioscience, Biocity, Nottingham, UK, "The quantitative assays and short run times on Jess enable us to generate data faster and be more confident in our results. Minneapolis, MN 55413 Jess begins by aspirating the separation matrix and then the stacking matrix into each capillary. The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. Translating Traditional Western Blots to Simple Western is Fast and Easy, Advancing Cell and Gene Therapies with Jess, Restoring Autophagy, Reversing Disease with Jess, Utilize Simple Westerns for Protein Analysis of Osteoarthritis Patient Samples, Utilizing Simple Western to Understand Neuronal Markers in Schizophrenia, Noelle Changes Her Brain Receptor Research Game with Wes, Mary Ups Her Data Point Count on Laser Capture Microdissection Samples with Wes, Miranda Sets a New Pace for Alzheimer's Research with Wes, Brian Cuts Time to Results and Solves His Membrane Protein Challenges with Wes, Jamie Keeps Things Greener with Simple Western, Mary Makes More Links Between Obesity and Cancer with NanoPro 1000, Emma Gets to Better Outcomes for Osteoarthritis Patients with Wes, Far Western Blot With Simple Western To Detect Protein Phosphorylation, Jane Gets Fast Answers for Cancer Research with Wes, Detecting Low Abundance Proteins in Precious Pediatric Cancer Samples with Wes, Lower Limit of Detection Advances Understanding of Metabolic Signaling in Human Muscle, Quantifying Protein Tyrosine Phosphatase in Platelets, Wes Zips Through Pharmacodynamic Biomarker Discovery Projects at the University of Glasgow, Wes Validates the Potential of RNA-based Metabolic Therapies At MiNA Therapeutics, Simple Western and the Race to Develop a Vaccine for the COVID-19 Coronavirus, Rebel without a Cause - Searching for the Origins of Parkinson's Disease with Wes, PROTAC Studies Take Off in Drug Discovery, and Jess is on Board, Jess Breaks New Quantitative Ground in New Chemical Entity Screening at TCG Lifesciences, Conducting Novel Therapeutics Research of Human Gliomas with Jess, Unraveling Neurodegenerative Diseases with Jess, Detect Phosphorylation of Proteins with RePlex, Elena Unlocks Immune Cell Potential with Simple Western and CRISPR/Cas9, Muhammad Uses Simple Western to Chart Stem Cell Signaling Pathways, Investigating Resolution of Inflammation with Jess, Delving into the Complexities of Endometrial Receptivity with Simple Western, Simple Western Individual Charge Reagents, Download PL6-0002 RevD Jess ProductBrochure.PDF, Download 043-125 RevD Jess Wes Abby-installation guide, Molecular weight (MW) ladder ranges from 2-440 kDa, <20% (total protein, chemiluminescence and fluorescence), Jess - Chemiluminescent & Fluorescent Western Blotting | ProteinSimple. Senior Lecturer in Drug Action, Neuroscience, University of Manchester, "One of the best advantages of using Wes is that it saves a lot of time, both in terms of hands-on time and in time to completion of the experiment. Explore our solutions for multiple applications - vaccines, monoclonal antibodies, recombinant proteins, cell or gene therapy. You'll be able to publish your results with confidence with effective normalization of your target protein expression, and if you're still doing traditional westerns, snap" get the picture with Jess's inbuilt plot imaging system. Analyze entire signaling pathways with high sensitivity multiplexing and total protein normalization. Postdoctoral Fellow, University of Texas Health Science Center, "We had been trying to study receptor proteins with traditional Westerns but it was frustratingwe just could not get it. VWR supports you in your autosampler vial selection process through on-site consultations with our Chromatography Specialists, and providing samples when needed. For . Try the improved Chemical Structure search through the new. Jess automated western blot systemshes like multiplexed Western blot meets ELISA in one. Novus Biologicals branded products are not currently available on biotechne.com and can be found at novusbio.com. Hi, my name is Jess - your complete protein analysis solution for automated Western Blotting Jess is a member of the Simple Western Family. Freeze cells in tubes from 1 to 5mL using the Thermo Scientific Mr. Frosty Freezing Container at nearly -1C/minute. Just load your samples and reagents into the microplate and Jess does the rest. Learn more about PROTEIN SIMPLE MS. We enable science by offering product choice, services, process excellence and our people make it happen. Jess automates the protein separation and immunodetection of traditional Western blotting, eliminating many of the tedious, error-prone steps. ACD branded products will be available on biotechne.com in the near future. Just load her protein normalization reagent into a row of wells on the plate, and she'll take care of the rest. With Jess, it's pipette, run & done! Don't miss out, order yours today! DM-001: Anti-Rabbit Detection Module Compatible with Jess, Abby, Wes, Peggy Sue and Sally Sue systems. VWR/Anachemia continues to be the undisputed leader when it comes to supplying laboratories conducting mineral analyses around the world VWR is proud of our years of experience providing choice and excellent service to the Industrial market from Food & Beverage, Petrochemical, Environmental Testing, Waste Water, Cosmetics, Consumer Goods, Agriculture and more See how the unique Nalgene Rapid-Flow membrane support system provides the last line of defense against contamination. 2023All rights reserved ", Jon Voutila, Ph.D., Protein analysis comes with many challenges, labor intensive protocols, increase time to result, and multiple hands-on steps increase user error and data variability. All Rights Reserved. Jess automates the protein separation and immunodetection of traditional Western blotting, eliminating many of the tedious, error-prone steps. If you're more familiar with capillary electrophoresis, you can see your results in a more traditional electropherogram view too. Or look at multiple targets and parameters simultaneously. All contact information provided shall also be maintained in accordance with our JESS WITH CHEMILUMINESCENCE JESS WITH STELLAR NIR JESS WITH STELLAR IR COMPETING FLUORESCENCE WESTERN BLOTTING TECHNOLOGY Jess with Chemiluminescence Jess with Stellar NIR / IR Why bother stripping and reprobing? All Rights Reserved. Stop, analyze and wow! Innovation in battery technology is becoming vital to facilitate the energy transition. ProteinSimple, the ProteinSimple logo and Jess are trademarks or registered trademarks of ProteinSimple. Just load your samples and reagents into the microplate and Jess separates your proteins by size, and precisely manages antibody additions, incubations, washes and even the . The products you use, the products you need, the suppliers you trust for chromatography. Quanta Biosciences and VWR are proud to fund a grant award for publication of research involving qPCR methodologies utilizing any Quanta Bioscience qPCR reagent in JoVE. Or detect high and low abundance proteins in the same sample, even when they have identical molecular weights. Our global footprint enables us to serve more than 300,000 customer locations and gives us extensive access to research laboratories and scientists in more than 180 countries. This had previously taken weeks and months using traditional Western blotting methods", Krishna C. Yalla, Ph.D., With protein normalization, you can take your protein load comparison and transform your data to effectively normalize your samples increasing your confidence in your data interpretation. With Jess, its pipette, run and done! You just load your samples and wait for results, and in the meantime, you can dedicate yourself to other activities. View all citations for the Simple Western platform. Copyright 2023 Bio-Techne. These goggles are comfortable and have good peripheral vision. ", Kazuya Machida, M.D., Ph.D., Please provide the information below and we will reply within one business day. Explore our solutions for multiple applications - vaccines, monoclonal antibodies, recombinant proteins, cell or gene therapy. ProteinSimple RePlex Module for Jess Supplier: ProteinSimple RP001 This RePlex Module provides all the reagents needed to remove primary and secondary antibodies in a RePlex assay with two immunoassays or immunoassay with Total Protein assay in a single run. Jesss protein normalization will give you the confidence you need in your analysis. Headquartered in Orchard Parkway, San Jose, California, ProteinSimple is helping scientists discover answers to real-world problems through protein and disease research. Tired of stripping and reprobing? FAX 612 656 4400, 15% Off Limited-time Savings on Your Reagents, Assays and Kits. Laboratory Coordinator, Department of Internal Medicine, East Tennessee State University, "The rapid, reproducible results on small amounts of tissue/cell lysates have allowed me to generate a more thorough data set on additional proteins, samples, conditions and brain regions all in the same amount, or even less time, as traditional Western blot. For your security, we have logged you out. Our global footprint enables us to serve more than 300,000 customer locations and gives us extensive access to research laboratories and scientists in more than 180 countries. From monoclonal and polyclonal antibodies to reagents, buffers and sera all spanning a wide range of applications. Jess gets you down to picogram-level sensitivity with just 3 L of starting material. Moving away from the tedious manual western blotting process, which can take up to two days, and introducing automation will speed up time to data and provide increased sensitivity and accuracy. Come back to fully analyzed western blotting results on 24 samples in 3 hours. Just load your samples and reagents into the microplate and Jess separates your proteins by size, and precisely manages antibody additions, incubations, washes and even the detection steps. A strong, vibrant research and development group is the lifeblood of all industries. New Avantor J.T.Baker premium conductive and non-conductive robotic tips deliver superior quality and reliable performance for results you can trust. Avantor supports end-to-end fluid management solutions including Masterflex peristaltic pumps and aseptic fluid transfer solutions that are reliable and customer-centric, helping bioprocessing manufacturers meet their research and production goals. For chemiluminescent detection, samples are first incubated with the primary antibody, followed by a secondary HRP conjugate, and finally chemiluminescent substrate. ", Elena Navarro-Guerrero, Ph.D., This allows us to use more advanced statistical techniques such as principal component analysis and hierarchal clustering to recognize key correlations in our research with ease", John K. Blackwood PhD, Now you can shop LabX to find antibodies, reagents, kits, and related tools for your research and clinical needs. The LabX marketplace has all the laboratory products, equipment, and accessories for your cell culture needs. Bio-Techne uses cookies to provide you with a great website experience. We empower you to make your next discovery by eliminating common protein analysis workflow challenges. Her fluorescent detection enables multiplexing, letting you maximize your time and sample. Just load your samples and reagents into the microplate, and Jess does HIGH THROUGHPUT Jess precisely controls sample loading, incubations and washes; she eliminates the inconsistencies and user-dependent variability that can be introduced during traditional Westerns. Her in-capillary protein normalization reagent is an easy way to see if your samples contain a consistent protein load and investigate experimental setup and user errors. Avantor carries a broad range of trusted products to help you meet the needs of your lab applications and protocols. The original product is no longer available. Senior Postdoctoral Researcher. Simply load your sample, antibodies and reagents into WHY SETTLE? ", Rachel Doidge Ph.D, Jess gives you four ways to analyze proteins. The field of neuroscience continues to offer groundbreaking insight into the most complex biological systems. Weve built our reputation on consistent, comprehensive mastery of day-to-day operations, allowing lab, clinical, and production environments to focus their high-value resources on core scientific priorities. Shop for the latest new and used equipment designed to meet the challenges of this emerging and promising field. Jess or Wes Separation Module, Protein Simple, Life Science Research Solutions, Products, and Resources, Controlled Environment and Cleanroom Solutions, How to Select the Right Chromatography Resin, Thermo Scientific Chromatography Columns and Consumables, Liquid Chromatography - Sample Preparation, Biopharma production chemicals & excipients, Laboratory Personal Protection Equipment (PPE) and Workwear Products, Laboratory Facilities Maintenance, Protection, and Hygiene Supplies, Building a Safe Work Environment with VWR, New Solutions - Controlled Environment and Cleanroom Products, Solutions by Industry Controlled Environment and Cleanroom Product, Safety and Controlled Environment Featured Brands, Controlled Environment & Cleanroom Sustainable Solutions, Masterflex Peristaltic Pump and Fluid Handling Solutions, Quality Products from Sheldon Manufacturing, Lab Thermometers & Temperature Measurement Equipment, Agilent Chemistries and Supplies Portfolio, PerkinElmer - Innovating for a Healthier World, Sartorius laboratory instruments, consumables and services, HALO Chromatography Columns and Consumables+-, The Avantor Value as a Medical Lab Partner, Reference materials Laboratory Products, Specialized Solutions for Cutting Applications, Contact Your Laboratory Furniture Specialist. Searching for key inflammation molecules", Kirstine Nolling Jensen, PhD Student, Easy access to products and protocols for research use only in the identification of 2019-nCoV based on Centers for Disease Control and Prevention (CDC) recommendations. It takes away so much of the pipetting and manipulation error. Simple Western immunoassays take place in a capillary.
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