They found that spirulina reduced total cholesterol (by 46.76 milligrams per deciliter (mg/dL)), low-density lipoprotein (LDL by 41.32 milligrams per deciliter), and triglycerides (by 44.23 milligrams per deciliter). View abstract. Bethesda (MD): National Library of Medicine (US); 2021. Br J Nutr 2011;105(11):1563-1571. Doubling up doesnt increase the benefits and may be harmful to the liver, says Todd SontagDO, a family medicine specialist with Orlando Health Physician Associates in Florida. View abstract. Marles RJ, Barrett ML, Barnes J, et al. Nielsen CH, Balachandran P, Christensen O, et al. In order to get 3.6 mg of astaxanthin one can eat 165 grams of salmon per day. Inflammation is an important part of the body's immune response. Im an indie content curator who does research daily, and quizzes myself on the important issues of the day. View abstract. For example, sometimes the ingredients in certain supplements can alter lab tests. Taking around 40 grams per day for an unknown period has been noted. Various remedies are available, but finding one, Read More Spirulina for Psoriasis: Can Spirulina Help With Psoriasis?Continue, From the appendix to the kidney, nothing that causes stones comes with admirable consequences. J Dermatol Sci 1998;16:226-230.. View abstract. Liu, X. and Osawa, T. Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food. Additionally, it includes crucial amino acids, the building blocks of proteins. For example, sometimes the ingredients in certain supplements can alter lab tests or have negative effects during surgery. U.S. Department of Agriculture. It's also used to lower the risk of stroke in certain people. Since it is a pure and natural food, you may safely take more, to suit your personal health program. Parisi V, Tedeschi M, Gallinaro G, et al. Goodwin TW. Determining the role of SGLT2 inhibition with Empagliflozin in the development of diabetic retinopathy. If you need to take both, zinc supplements should be taken at least two hours before or after taking penicillamine. Comp Biochem Physiol C.Toxicol Pharmacol 2004;139(1-3):99-110. Di Mascio, P., Devasagayam, T. P., Kaiser, S., and Sies, H. Carotenoids, tocopherols and thiols as biological singlet molecular oxygen quenchers. Please don't give children supplementsincluding spirulinawithout discussing this with their pediatrician first. View abstract. 2003;4(3):207-216. Consider working with a team that includes a registered dietitian nutritionist (RD or RDN) and perhaps one that's a Board Certified Specialist in Obesity and Weight Management (CSOWM). However, even if supplements are third-party tested, that doesn't mean they are necessarily safe for all or effective in general. We have 11 reasons why you should add it to your. It is also jam-packed with anti-fatigue and anti-inflammatory properties. View abstract. The algae may harbor toxins if it grows in a body of water thats polluted with heavy metals, bacteria, or harmful particles called microcystins (2). Spirulina has GLA - great for arthritis. Taking green tea with iron can reduce the absorption of the mineral. J Herb.Pharmacother. 2012;59(1):43-47. View abstract. Future.Cardiol 2009;5(4):333-342. A common question among dietary consumers is, does Spirulina contain Astaxanthin? Med Sci Sports Exerc. The mineral copper is involved in energy production and helps create your connective tissue, which gives structure to the body. 2007;50:244-48. Clin Microbiol Infect. It may provide antioxidant, anti-inflammatory, and immune-boosting benefits. USDA. J Sports Med Phys Fitness. This information may not fit your specific health circumstances. View abstract. Naeini F, Zarezadeh M, Mohiti S, Tutunchi H, Ebrahimi Mamaghani M, Ostadrahimi A. Spirulina supplementation as an adjuvant therapy in enhancement of antioxidant capacity: a systematic review and meta-analysis of controlled clinical trials. Chalyk NE, Klochkov VA, Bandaletova TY, Kyle NH, Petyaev IM. Suganuma, K., Nakajima, H., Ohtsuki, M., and Imokawa, G. Astaxanthin attenuates the UVA-induced up-regulation of matrix-metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. View abstract. Yousefi R, Saidpour A, Mottaghi A. Spirulina grown in controlled environments is lower in microcystins, as scientists have developed methods to remove this compound, as well as limit its production (8, 9). Spirulina, meanwhile, may increase the number of new neurons that survive while protecting your brain against the inflammation associated with neurodegenerative diseases. While it has several benefits, you may be wondering if it comes with any side effects. Arzneimittelforschung. Not getting enough B12 can cause tiredness, memory loss, depression, and even different types of anemia. It's important to note that while spirulina may impact these outcomes, essential issues include exploring your current overall way of eating, your movement (exercise), and other equally important issues like addressing your emotional health. Djordjevic B, et al. Astaxanthin has proved helpful in the treatment of some diseases such as Alzheimer's, Parkinson's, stroke, high cholesterol and other conditions. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. View abstract. Tanaka T, Morishita Y, Suzui M, et al. It contains roughly the same amount of protein as meat. But zinc can interact with numerous medications including: Certain antibioticsspecifically quinolone antibiotics (like Cipro) and tetracycline antibiotics (like Achromycin and Sumycin)interact with zinc in the gastrointestinal tract and don't allow the absorption of both the zinc and the antibiotic. There've been several studies on test tube cells or animals that aren't humans. Vitamin Keven in foods such as kale, lettuce, broccoli, and chickpeascan counteract a blood thinners benefits. Jyonouchi H, Sun S, Tomita Y, et al. Spirulina is a blue-green algae from the genus Arthrospira ("arthro" roughly means "joint," and "spira" means "spiral"). Chew BP, Park JS, Wong MW, et al. Cancer Lett. Omega-3 to omega-6 fatty acids in Spirulina are present in a ratio of roughly 1.5 to 1. Health.com uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. It's also responsible for producing protein and creating energy . J Photochem.Photobiol.B 1994;26(3):283-285. Some "wild-crafted" spirulina products may have been grown in water contaminated with heavy metals (mercury, lead, arsenic, cadmium) or other pollutants. View abstract. How to report a problem with dietary supplements. Int J Sports Med. Others may require additional monitoring or dosage changes. View abstract. Methods Mol.Biol. Astaxanthin Benefits, Foods, Dosage and Side Effects Zinc is a mineral that has numerous roles, including in immunity, protein creation, wound healing, DNA creation, and sense of taste and smell. Bito T, Okumura E, Fujishima M, Watanabe F. Potential of chlorella as a dietary supplement to promote human health. Symptoms of negative interactions can include fatigue, yellowing of the skin, and severe muscle pain. J Photochem.Photobiol.B 12-1-2006;85(3):205-215. Iron supplements are typically recommended for people who have iron-deficiency anemia, cancer, and certain gastrointestinal disorders, as well as for those who are pregnant. Discard as indicated by the "use by" date on the packaging. 2002;30(1):73-84. View abstract. Here are. Mixing medications and dietary supplements can endanger your health. Karppi, J., Rissanen, T. H., Nyyssonen, K., Kaikkonen, J., Olsson, A. G., Voutilainen, S., and Salonen, J. T. Effects of astaxanthin supplementation on lipid peroxidation. Metabolic syndrome happens when you have high blood pressure, high blood sugar, high cholesterol, and excess fat around your waist (excess abdominal fat). Plant Foods Hum Nutr. U.S. Food & Drug Administration. Complement Ther Med. Some supplements may be contaminated by toxins. Evid Based Complement Alternat Med. Asia Pac J Clin Nutr. Whole grains, fruit, and vegetables help increase your body's antioxidant capacity and reduce inflammation. Coenzyme Q10, or CoQ10, is one of the antioxidants that your body naturally creates. Astaxanthin is a red pigment found in marine animals and microorganisms, whereas lutein and zeaxanthin are yellow pigments found in vegetables and fruits. Miki, W., Hosoda, K., Kondo, K, and Itakura, H. Astaxanthin-containing drink. View abstract. It might be useful as a treatment for. View abstract. Learn more about its usage, effectiveness and benefits. Spirulina is a blue-green alga that naturally grows in salty lakes and oceans in subtropical climates. View abstract. An example of a blood pressure drug is the calcium channel blocker diltiazem (Cardizem). There are two types of inflammation - regular and silent. Kupcinskas L, Lafolie P, Lignell A, et al. Here are some supplement combinations that you should talk to a healthcare provider aboutand what you what you might need to do if you take both. Int J Sport Nutr Exerc Metab 2005;15:401-12. View abstract. It's important to note that obesity can be closely tied to the determinants of health and health disparities which are also essential to address. I read a hilarious Reddit feed the other day about the benefits of moringa vs spirulina. Liu, X., Shibata, T., Hisaka, S., and Osawa, T. Astaxanthin inhibits reactive oxygen species-mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism. Gupta RC, Chang D, Nammi S, Bensoussan A, Bilinski K, Roufogalis BD. Br J Nutr 2007;98(1):38-44. Higuera-Ciapara, I., Felix-Valenzuela, L., and Goycoolea, F. M. Astaxanthin: a review of its chemistry and applications. Part 182 -- Substances Generally Recognized As Safe. J.Med.Food 2003;6(1):51-56. Dont miss these signs your body is running low on key vitamins. Which Vitamins Are Dangerous to Take at the Same Time? - LIVESTRONG.COM Read our, Supplements That Can Interact With Medications, Prenatal Vitamins: Benefits and When You Should Take Them, The 10 Best Collagen Supplements, According to a Dietitian, The 6 Best Supplements for Weight Gain of 2023, According to a Dietitian, Herbs You Should Avoid Mixing With Heart Meds, Before You Buy Magnesium Supplements From TikTok, Heres What You Need to Know, The Top Health Benefits of Stinging Nettle, 5 Supplements You May Need if Youre on the Keto Diet, people take melatonin supplements to help with sleep, Dietary guidelines for Americans 2020-2015, Mixing medications and dietary supplements can endanger your health. Okada, Y., Ishikura, M., and Maoka, T. Bioavailability of astaxanthin in Haematococcus algal extract: the effects of timing of diet and smoking habits. View abstract. While spirulina has most of the amino acids that your body needs, it doesn't have enough of some of them. View abstract. Summary Spirulina is a type of blue-green algae that people can take as a dietary supplement. However, if you take more than one or take a supplement while on a medication, there might be a risk for negative interactions. Both Spirulina and Astaxanthin have numerous benefits. J Nutr 2005;135(11):2507-2511. While Astaxanthin is derived from the microalga Haematococcus Pluvialis, it has a potent use as a dietary supplement for humans. Clin Med (Lond). Does Spirulina Have Any Side Effects? But there are certain combinations that shouldn't be taken. Registered dietitian nutritionists can help you build your toolkit and your capacity. That's why adding lysine from foods is important for a balanced, Health enthusiasts have long raved about the countless benefits of wheatgrass, and for good reason. Metabolic syndrome is a collection of symptoms like high blood sugar, high blood pressure, high triglycerides, low HDL ("good cholesterol"), and increased waist circumference, which can create more severe health problems. Here are 7 science-backed benefits of eating, Your body can also make arginine in addition to getting it from food sources, so deficiencies are rare. Dietary supplements are minimally regulated by the FDA and may or may not be suitable for you. Find out whichvitamins are a waste of money and could even be dangerous. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations. Astaxanthin supplementation does not attenuate muscle injury following eccentric exercise in resistance-trained men. For those taking blood thinners or who have bleeding disorders, spirulina may be dangerous because it could lessen your bloods ability to clot, causing more bruising and bleeding (2). Spirulina is accessible as a liquid, powder, tablet, and capsule. The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes. In addition, they can help you build your toolkit and capacity to help you feel better. Spirulina has an anticoagulant effect, meaning that it can thin your blood and increase the length of time it takes for blood to clot (2, 16). Appl Microbiol Biotechnol 1997;48:351-6. Spirulina for Psoriasis: Can Spirulina Help With Psoriasis? 2010;26(5):457-467. Mol Nutr Food Res 2006;50(11):991-995. All rights reserved. View abstract. Astaxanthin is derived from the micro-algae Haematococcus pluvialis, Your email address will not be published. Avoid using this product if you are pregnant or anticipate getting pregnant soon. FEBS Lett. Blood pressure medicine. To be safe, people with allergies should avoid this supplement or reach out to a doctor before using it (21). Although Spirulina capsules vs tablets are more complex and compact, they may go through the system undigested or only partially digested because our system can absorb all forms. 2021;24(1):92-97. View abstract. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Avoid spirulina if you're allergic or sensitive to it or any of its ingredients. Spirulina has a chlorophyll content that is over ten times higher than that of common vegetables. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. U.S. Food & Drug Administration. J Am Coll Nutr. View abstract. National Institutes of Health National Center for Complementary and Integrative Health. Effect of spirulina supplementation on systolic and diastolic blood pressure: systematic review and meta-analysis of randomized controlled trials. Both highlight the health benefits of algae, producing a range of health-improving effects. 2021;16(11):2057-2067. doi:10.1021/acschembio.1c00568. You might even take a combination of supplements. This could change the effects and side effects of these medications. Bloomer, R. J. Clotting helps prevent excessive bleeding or bruising when youre injured (17). Continuous astaxanthin intake reduces oxidative stress and reverses age-related morphological changes of residual skin surface components in middle-aged volunteers. Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus. Mahmoud, F. F., Haines, D. D., Abul, H. T., Abal, A. T., Onadeko, B. O., and Wise, J. But, by strengthening the NK cells in people with autoimmune conditions, this algae may exacerbate these conditions. In vitro effects of astaxanthin combined with ginkgolide B on T lymphocyte activation in peripheral blood mononuclear cells from asthmatic subjects. Dr. Bob's BLOG is not intended as medical advice. Human research has shown that ashwagandha can stimulate the immune system. View abstract. Scientists have studied, but not necessarily proven, spirulina's impact on different areas of health, including but not limited to the following: We'll explore what the science says about spirulina's effectiveness for these health outcomes. Typically, Spirulina is sold as a powder or pill. View abstract. Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease. Wang, H. Q., Sun, X. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. 2018;27(2):341-346. The B12 in spirulinapseudovitamin B12is in a different form than the type that's typically absorbable by your body. It also increased the "good" cholesterol or high-density lipoprotein (HDL by 6.06 milligrams per deciliter). Nutrients. Dr. Mercola appeared on Dr. Oz.s television program about Astaxanthin, a powerful antioxidant and anti-inflammatory, which I have written about before. However, the most effective way to go about long-term change in these areas is by exploring and addressing your overall eating patterns and movement over time and your social connections, which can all profoundly affect your health and well-being. J Agric Food Chem 6-28-2006;54(13):4593-4599. It is also available in a variety of supplement forms, though taking them might not be advised. Biomed Res Int. Physiol Rep 2021;9(11):e14887. View abstract. Researchers have shown that spirulina has some effects on increasing antioxidant levels in the body and reducing blood pressure, blood sugar, and cholesterol levels. Garlic thins out the blood, and if you take a daily baby aspirin or a blood thinner such as Coumadin (warfarin), it could be risky, Dr. Glatter says. This mineral supports normal daily functions like muscle use and your heartbeat. Asian J Androl 2005;7:257-62.. View abstract. The effects of supplements vary from person to person and depend on many variables, including type, dosage, frequency of use, and interactions with current medications. Scientists conducted a meta-analysis of spirulina's effects on cholesterol levels that had seven controlled trials for a total of 522 total people. This popular supplement is a plant native to Europe that has yellow, star-shaped flowers. 9-28-2009;283(1):108-117. Nihon Ganka Gakkai Zasshi 2009;113(3):403-422. View abstract. A., Glamm, J. E., and Failla, M. L. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. Last medically reviewed on September 10, 2021. Dosage: How Much Spirulina Should I Take? An allergic reaction may be possible in those allergic to spirulina. Here are 10 science-based benefits of green tea extract. Side effects and downsides Although spirulina is generally considered safe, it may have some side effects and drawbacks especially for people with certain health conditions ( 2, 4 ). View abstract. Wang, X., Willen, R., and Wadstrom, T. Astaxanthin-rich algal meal and vitamin C inhibit Helicobacter pylori infection in BALB/cA mice. Rich in many nutrients. In severe cases, reactions can be fatal (20). You wont start to feel different in your energy levels for about one to three weeks. Scientists are still figuring it out. Some people may be allergic to spirulina. View abstract. Astaxanthin supplementation does not augment fat use or improve endurance performance. View abstract. I wont go, Read More Moringa Vs Spirulina: Which Should You Choose?Continue, Trying to boost your health? Boswellia: Benefits, Side Effects, Dosage, and Interactions To a certain extent, oil rich in docosahexaenoic acid (DHA) obtained from Schizochytrium sp. Spirulina: Health Benefits, Uses, Side Effects, Dosage J Nutr Sci Vitaminol. Again, why did spirulina do this? Palozza, P., Torelli, C., Boninsegna, A., Simone, R., Catalano, A., Mele, M. C., and Picci, N. Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells. URL: https://www.astaxanthin.org. Nakanishi R, Kanazashi M, Tanaka M, Tanaka M, Fujino H. Impacts of astaxanthin supplementation on walking capacity by reducing oxidative stress in nursing home residents. Always consult a medical doctor or other medical professional when you consider it necessary. The Future of Food: Growing Your Own Algae? Our products are not meant to diagnose, treat, cure or prevent any disease. Mol Nutr Food Res 2011;55(1):150-165. Its also commercially produced for use in food and supplements (1, 2). It's also a source of protein, but it lacks high enough levels of some of the amino acids that your body needs to function at its best (unless you have a medical condition where you need to avoid specific amino acids, like phenylketonuria or "PKU"). In addition, animal research has shown that ashwagandha can decrease the effectiveness of the immunosuppression caused by cyclophosphamide, a drug used to treat cancer and nephrotic syndrome. View abstract. Andersen LP, Holck S, Kupcinskas L, et al. Antimicrob.Agents Chemother. Karkos PD, Leong SC, Karkos CD, Sivaji N, Assimakopoulos DA. Biosci.Biotechnol.Biochem 2007;71(4):893-899. Nutr Res 2022;99:40-50. So, where does Astaxanthin come from? View abstract. That's why knowing the potential interactions of supplements is important. It's recommended that people at high risk for magnesium deficiency who take calcium supplements take the calcium at bedtime instead of during a meal. Liu, X., Yamada, N., and Osawa, T. Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts. J.Pharmacol.Sci. 2002;21:489. But if you mix it with green tea, black tea, or curcumin supplements, your body wont absorb the mineral. Supplement Combinations to Avoid Supplements can have health benefits, but they may also have health risks. Earnest CP, Lupo M, White KM, Church TS. Seaweed is highly nutritious and an increasingly popular ingredient in cuisines all over the world.